Computational approaches to study molecular pathogenesis and intervention of infectious diseases

Reconciling Multiple Connectivity Scores for Drug Repurposing.

The basis of several recent methods for drug repurposing is the key principle that an efficacious drug will reverse the disease molecular 'signature' with minimal side effects. This principle was defined and popularized by the influential …

sRNA discovery

Discovering unique pathogenic sRNA in infected hosts

Host-responses to infection

Characterizing host response to infection and host-directed interventions

Cutting edge: Vitamin D regulates lipid metabolism in Mycobacterium tuberculosis infection