molecular-evolution

Molecular Evolution and Phylogeny

The Staphylococcus aureus cystine transporters, TcyABC and TcyP, facilitate nutrient sulfur acquisition during infection

Computational approaches for understanding host–pathogen biology

Conservation and modularity in the pan-bacterial psp stress response system

An integrative computational evolutionary approach to accelerate the discovery of molecular targets in prevalent under-studied pathogens

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Bacterial stress response

Studying stress response systems using molecular evolution and phylogenetics.

Using computational appraches to understand host-pathogen biology

Variations on a theme: evolution of the phage-shock-protein system in Actinobacteria

The Psp system of Mycobacterium tuberculosis integrates envelope stress-sensing and envelope-preserving functions

The bacterial envelope integrates essential stress-sensing and adaptive functions; thus, envelope-preserving functions are important for survival. In Gram-negative bacteria, envelope integrity during stress is maintained by the multi-gene Psp …