tree-of-life

The phage shock protein (PSP) envelope stress response: discovery of novel partners and evolutionary history

Bacterial phage shock protein (PSP) systems stabilize the bacterial cell membrane and protect against envelope stress. These systems have been associated with virulence, but despite their critical roles, PSP components are not well characterized …

MolEvolvR: a web-app for characterizing proteins using molecular evolution and phylogeny

Studying proteins through the lens of evolution can reveal conserved features, lineage-specific variants, and their potential functions. MolEvolvR (https://jravilab.org/molevolvr) is a novel web-app enabling researchers to visualize the molecular …

Computational evolutionary approaches

Integrating molecular evolution and comparative genomics to achieve comprehensive, multiscale characterization of bacterial proteins and genomic features.

Bacterial Stress Response

Studying stress response systems using molecular evolution and phylogenetics.