S-layers: the proteinaceous multifunctional armours of Gram-positive pathogens.

The glutathione import system satisfies the Staphylococcus aureus nutrient sulfur requirement and promotes interspecies competition

Sulfur is an indispensable element for proliferation of bacterial pathogens. Prior studies indicated that the human pathogen, Staphylococcus aureus utilizes glutathione (GSH) as a source of nutrient sulfur; however, mechanisms of GSH acquisition are …

MolEvolvR: a web-app for molecular evolution and phylogeny

We will discuss the alpha version of their new easy-to-use interactive webapp: MolEvolvR, for characterizing proteins using molecular evolution and phylogeny. We will begin by demonstrating the power of MolEvolvR using the panbacterial stress response system, PSP (phage shock protein), as an example. Then, we will anyone can use this app to study their protein(s) of interest. PSP app: (bioRxiv 2020) MolEvolvR app: (currently, alpha-version)

Discovery of a predominant and distinct lineage of Mycobacterium tuberculosis in Brazilian indigenous population.

After nearly a century of vaccination and six decades of drug therapy, tuberculosis (TB) kills more people annually than any other infectious disease. Substantial challenges to disease eradication remain among vulnerable and underserved populations. …

Computational evolutionary approaches

Integrating molecular evolution and comparative genomics to achieve comprehensive, multiscale characterization of bacterial proteins and genomic features.

sRNA discovery

Discovering unique pathogenic sRNA in infected hosts

Phage-shock-protein (Psp) Envelope Stress Response: Evolutionary History & Discovery of Novel Players

Computational evolutionary approaches for understanding pathogen proteins and genomes

Computational evolutionary approaches to characterize bacterial proteins

The Staphylococcus aureus cystine transporters, TcyABC and TcyP, facilitate nutrient sulfur acquisition during infection