pathogenic-features

We will discuss the alpha version of their new easy-to-use interactive webapp: MolEvolvR, for characterizing proteins using molecular evolution and phylogeny. We will begin by demonstrating the power of MolEvolvR using the panbacterial stress response system, PSP (phage shock protein), as an example. Then, we will anyone can use this app to study their protein(s) of interest. PSP app: jravilab.shinyapps.io/psp-evolution (bioRxiv 2020) MolEvolvR app: jravilab.org/molevolvr (currently, alpha-version)

After nearly a century of vaccination and six decades of drug therapy, tuberculosis (TB) kills more people annually than any other infectious disease. Substantial challenges to disease eradication remain among vulnerable and underserved populations. …

Integrating molecular evolution and comparative genomics to achieve comprehensive, multiscale characterization of bacterial proteins and genomic features.