Bacterial Stress Response


I started working on bacterial stress responses during my postdoctoral research at Rutgers University, I continue to focus on using computational evolutionary approaches to study various facets of pathogen biology including:

  • delineating the molecular mechanism underlying a newly identified stress response operon in the tubercle bacterium involving the phage-shock-proteins (psp);
  • unraveling the evolution of bacterial stress response systems (psp) across the tree of life using protein sequence-structure-function relationships;
  • reconstructing and analyzing the mycobacterial sigma factor regulatory network.


  • Samuel Chen (Alumni)


  • Marila Gennaro (Rutgers)
  • L Aravind (NCBI, NIH)
  • Vivek Anantharaman (NCBI, NIH)
Janani Ravi
Assistant Professor

My research interests include computational pathogenomics and host-directed drug-repurposing.