Studying lipid metabolism deregulation in TB


We also studied host responses to M. tuberculosis infection using computational approaches:

  • characterizing the transcriptional response in infected macrophages under various small molecule perturbations using RNA-Seq analysis;
  • understanding the dysregulation of lipid metabolism in M. tuberculosis-infected macrophages using dynamic Bayesian model and statistical analyses of heterogeneous single-cell populations.


Rutgers University

  • Marila Gennaro
  • Sanjay Tyagi
  • Eduardo Sontag (now in North Eastern)

Tulane University

  • Deepak Kaushal

Knowledge Synthesis

  • Hugh Salamon
Janani Ravi
Assistant Professor

My research interests include computational pathogenomics and host-directed drug-repurposing.